Parathyroid carcinoma in tertiary hyperparathyroidism

Parathyroid carcinoma presenting as tertiary hyperparathyroidism.

A case of malignant transformation in established secondary hyperparathyroidism presenting as tertiary hyperparathyroidism is reported. Although rare, this occurrence has important medical and surgical implications.

Intrathyroidal parathyroid hyperplasia in tertiary hyperparathyroidism

We report herein a case of intrathyroidal parathyroid hyperplasia in a patient with tertiary hyperparathyroidism. The patient was recommended for parathyroidectomy due to sustained hypercalcemia after kidney transplantation. Preoperative radiologic evaluations showed a benign-looking thyroid mass and three enlarged parathyroid glands. Intraoperative intact parathyroid hormone (iPTH) level and f...

Parathyroid carcinoma in familial hyperparathyroidism.

Two families with hereditary hyperparathyroidism are described. One member of each family developed a parathyroid carcinoma. In one case this recurred locally and metastasised. This patient showed hyperplasia of one of the three other parathyroid glands. It is possible that the different parathyroid lesions found in familial hyperparathyroidism may be the result of a progression from hyperplasi...

Hyperparathyroidism due to parathyroid carcinoma.

Concurrent Parathyroid Carcinoma and Hyperplasia in Hyperparathyroidism

To the Editor, Parathyroid carcinoma is a rare disease that accounts for less than 1% of all hyperparathyroidism [1]. The incidence of parathyroid carcinoma is extremely low, although the apparent incidence of hyperparathyroidism increased after the introduction of multi-channel autoanalyzers. If increased serum calcium and parathyroid hormone (PTH) levels are sustained postoperatively, metasta...